One key mechanism through which thyroid hormones affect energy metabolism is the transcriptional induction of mitochondrial uncoupling proteins as discussed earlier slide 631 uncoupling proteins mediate the conversion of metabolic energy to heat and therefore increase the burn rate of glucose and other energy rich substrates. The robust th regulation of components of lipid and carbohydrate metabolism as well as energy expenditure provides attractive therapeutic targets for a range of metabolic disorders 15 270 a number of thyroid hormone analogs have been developed for cholesterol reduction and weight loss 28 31 205 227 . Ghrelin is produced in the stomach in addition to its role in long term regulation of energy metabolism it is involved in the short term regulation of feeding these hormones have important roles in energy homeostasis glucose and lipid metabolism reproduction cardiovascular function and immunity. Start studying hormonal regulation of energy metabolism learn vocabulary terms and more with flashcards games and other study tools. 604 chapter 21 the endocrine system regulation of energy metabolism and growth the ultimate fate of consumed molecules depends on their chemi cal nature and the bodys needs at the time of consumption as described next
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