Dopamine glutamate interactions in the basal ganglia synthesizes this recent research from the level of receptor molecules all the way to complex behaviours and disease current insights from research on individual neurons and synapses detailed circuit analysis and learning and action functions of the basal ganglia are presented against a historical perspective. Dopamine glutamate interactions in the basal ganglia frontiers in neuroscience by crc press 2011 12 14 isbn kostenloser versand fur alle bucher mit versand und verkauf duch amazon. Dopamine glutamate interactions in the basal ganglia frontiers in neuroscience book 49 kindle edition by susan jones download it once and read it on your kindle device pc phones or tablets use features like bookmarks note taking and highlighting while reading dopamine glutamate interactions in the basal ganglia frontiers in neuroscience book 49. In an attempt to formulate a working hypothesis of basal ganglia functions arguments are considered suggesting that the basal ganglia are involved in a process of response selection ie in the facilitation of wanted and in the suppression of unwanted behaviour the meso accumbal dopamine system is considered to mediate natural and drug induced reward and sensitization the meso . Current antiparkinsonian therapies focus on either replacing dopamine via precursor l dopa administration or directly stimulating postsynaptic dopamine receptors with dopamine agonists unfortunately this approach is associated with numerous side effects and these drugs lose efficacy with disease progression this article reviews recent evidence which suggests that negative modulation of
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